Øystein Bruserud Selected Research

Acute Myeloid Leukemia (Acute Myelogenous Leukemia)

12/2023	High Mitochondrial Protein Expression as a Potential Predictor of Relapse Risk in Acute Myeloid Leukemia Patients with the Monocytic FAB Subtypes M4 and M5.
8/2023	Vacuolar ATPase Is a Possible Therapeutic Target in Acute Myeloid Leukemia: Focus on Patient Heterogeneity and Treatment Toxicity.
7/2023	Casein Kinase 2 (CK2): A Possible Therapeutic Target in Acute Myeloid Leukemia.
1/2023	Pretransplant systemic metabolic profiles in allogeneic hematopoietic stem cell transplant recipients - identification of patient subsets with increased transplant-related mortality.
1/2022	Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia.
8/2021	Effects of the Autophagy-Inhibiting Agent Chloroquine on Acute Myeloid Leukemia Cells; Characterization of Patient Heterogeneity.
5/2021	Therapeutic Use of Valproic Acid and All-Trans Retinoic Acid in Acute Myeloid Leukemia-Literature Review and Discussion of Possible Use in Relapse after Allogeneic Stem Cell Transplantation.
4/2021	Proteomic Studies of Primary Acute Myeloid Leukemia Cells Derived from Patients Before and during Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid and Valproic Acid.
3/2021	The Constitutive Extracellular Protein Release by Acute Myeloid Leukemia Cells-A Proteomic Study of Patient Heterogeneity and Its Modulation by Mesenchymal Stromal Cells.
1/2021	p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy.

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Øystein Bruserud Research Topics

Disease

89	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2023 - 01/2002
35	Neoplasms (Cancer) 08/2023 - 05/2004
28	Leukemia 07/2023 - 01/2002
17	Hematologic Neoplasms (Hematological Malignancy) 01/2023 - 05/2004
13	Cytopenia 11/2011 - 06/2002
12	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2023 - 03/2010
10	Inflammation (Inflammations) 01/2023 - 02/2012
9	Infections 01/2023 - 07/2006
6	Acute-Phase Reaction 01/2022 - 09/2002
5	Multiple Myeloma 12/2023 - 05/2004
5	Chromosome Aberrations (Chromosome Abnormalities) 03/2015 - 02/2002
4	Bronchiolitis Obliterans Syndrome 01/2023 - 08/2014
4	Sepsis (Septicemia) 01/2023 - 11/2011
3	Bacteremia 01/2023 - 01/2018
3	Fibrosis (Cirrhosis) 01/2023 - 10/2013
3	Hematologic Diseases (Blood Diseases) 06/2022 - 01/2015
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 05/2019 - 05/2003
3	Thrombocytopenia (Thrombopenia) 01/2019 - 08/2006
3	Thrombosis (Thrombus) 01/2019 - 07/2015
3	Venous Thrombosis (Deep-Vein Thrombosis) 01/2019 - 07/2015
3	Weight Gain 11/2016 - 01/2010
3	Bone Marrow Failure Disorders 10/2013 - 10/2004
3	Bacterial Infections (Bacterial Infection) 11/2011 - 09/2002
3	Sarcoma (Soft Tissue Sarcoma) 01/2005 - 04/2004
3	Leukopenia 11/2004 - 10/2002
2	Squamous Cell Carcinoma of Head and Neck 04/2024 - 10/2020
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 08/2023 - 01/2023
2	Cytokine Release Syndrome 01/2022 - 11/2021
2	Fever (Fevers) 11/2021 - 10/2018
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2021 - 07/2020
2	Neoplasm Metastasis (Metastasis) 01/2021 - 12/2020
2	Disease Progression 01/2021 - 12/2018
2	Philadelphia Chromosome 05/2019 - 01/2018
2	Myeloproliferative Disorders (Myeloproliferative Disorder) 01/2018 - 08/2006
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2018 - 01/2018
2	Carcinogenesis 10/2017 - 03/2011
2	Lymphopenia (Lymphocytopenia) 12/2008 - 10/2002
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 02/2006 - 02/2006
2	Febrile Neutropenia 10/2002 - 06/2002

Drug/Important Bio-Agent (IBA)

27	CytokinesIBA 04/2024 - 05/2003
14	Proteins (Proteins, Gene)FDA Link 08/2023 - 07/2004
12	Biomarkers (Surrogate Marker)IBA 10/2020 - 02/2013
11	Interleukin-6 (Interleukin 6)IBA 04/2024 - 01/2010
8	Valproic Acid (Depakote)FDA LinkGeneric 05/2021 - 01/2006
7	ChemokinesIBA 01/2023 - 07/2006
7	Tretinoin (Retinoic Acid)FDA LinkGeneric 05/2021 - 01/2006
5	Phosphotransferases (Kinase)IBA 01/2019 - 02/2006
5	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2017 - 01/2002
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2011 - 07/2004
4	C-Reactive ProteinIBA 01/2022 - 07/2020
4	Sirolimus (Rapamycin)FDA Link 01/2019 - 03/2008
4	Histone Deacetylase InhibitorsIBA 02/2013 - 09/2007
3	LipidsIBA 01/2023 - 06/2022
3	AntibodiesIBA 11/2021 - 02/2010
3	Protein Isoforms (Isoforms)IBA 01/2021 - 04/2006
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2020 - 06/2007
3	ProteomeIBA 03/2020 - 11/2016
3	Immunomodulating AgentsIBA 01/2020 - 01/2019
3	Interleukin-8 (Interleukin 8)IBA 10/2018 - 04/2004
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 09/2018 - 03/2010
3	Metalloproteases (Metalloproteinases)IBA 01/2018 - 07/2015
3	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 01/2009 - 12/2002
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 04/2024 - 10/2004
2	Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA 08/2023 - 01/2018
2	Casein Kinase II (Casein Kinase 2)IBA 08/2023 - 07/2023
2	Messenger RNA (mRNA)IBA 08/2023 - 09/2013
2	Adenosine Triphosphatases (ATPase)IBA 08/2023 - 01/2018
2	Peptides (Polypeptides)IBA 01/2023 - 01/2023
2	Taurine FDA Link 01/2023 - 01/2015
2	SteroidsIBA 01/2023 - 06/2022
2	Amino Acids FDA Link 01/2023 - 01/2018
2	Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA 04/2022 - 01/2021
2	Therapeutic UsesIBA 05/2021 - 12/2007
2	InterleukinsIBA 07/2020 - 03/2011
2	Acute-Phase Proteins (Acute-Phase Protein)IBA 07/2020 - 07/2020
2	Interferon-alpha (Interferon Alfa)IBA 07/2019 - 08/2006
2	Transcription Factors (Transcription Factor)IBA 12/2018 - 12/2007
2	Syk KinaseIBA 01/2018 - 01/2018
2	Tyrosine (L-Tyrosine)FDA Link 01/2018 - 02/2006
2	NucleophosminIBA 12/2016 - 03/2015
2	AntigensIBA 06/2015 - 12/2008
2	ConnexinsIBA 03/2015 - 01/2010
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 08/2014 - 12/2006
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 02/2012 - 09/2002
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 09/2011 - 02/2006
2	Complementary DNA (cDNA)IBA 03/2009 - 05/2006
2	Interleukin-2 (IL2)IBA 06/2007 - 10/2002
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 06/2007 - 10/2004
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2005 - 01/2005
1	Interleukin-1 (Interleukin 1)IBA 04/2024
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 04/2024
1	Ciliary Neurotrophic Factor (CNTF)IBA 04/2024

Therapy/Procedure

34	Drug Therapy (Chemotherapy) 12/2023 - 06/2002
31	Therapeutics 08/2023 - 01/2002
30	Stem Cell Transplantation 12/2023 - 10/2003
11	Immunotherapy 01/2022 - 10/2002
4	Transplantation 01/2023 - 03/2010
4	Hematopoietic Stem Cell Transplantation 01/2023 - 02/2016
3	Autologous Transplantation 09/2011 - 10/2003
2	Aftercare (After-Treatment) 07/2010 - 02/2002